Opportunity Information: Apply for RFA MD 21 004
The National Institutes of Health (NIH) funding opportunity titled "Understanding and Addressing the Impact of Structural Racism and Discrimination on Minority Health and Health Disparities (R01 Clinical Trial Optional)" (Funding Opportunity Number: RFA-MD-21-004) supports research projects that examine how structural racism and discrimination (SRD) contribute to minority health outcomes and persistent health disparities, and projects that test ways to reduce those harms. The mechanism is an R01 grant, and clinical trials are allowed but not required, which means applicants can propose either observational studies, intervention studies, or a mix, as long as the work directly advances understanding of SRD and/or evaluates strategies to address it in ways that improve minority health or reduce disparities.
The opportunity is explicitly organized around two main research directions. First, NIH is interested in observational research that clarifies the pathways through which structural racism and discrimination operate, including how these forces create, maintain, or worsen unequal health outcomes over time. This can include studying policies, institutional practices, neighborhood and environmental conditions, access to education and employment, housing patterns, and other systemic drivers that shape health risks and healthcare access for minority populations. Second, NIH seeks intervention research that targets SRD itself, meaning projects that go beyond documenting disparities and instead test approaches intended to reduce discriminatory structures or mitigate their effects, with outcomes tied to measurable improvements in minority health or reductions in health disparities.
Eligibility is broad and includes many types of U.S.-based organizations and government entities. Eligible applicants include state, county, and city/township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities and Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (as long as they are not institutions of higher education when categorized that way); for-profit organizations other than small businesses; small businesses; and other organizations. The announcement also highlights additional eligible applicant categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISISs). Faith-based and community-based organizations are also included, as are eligible federal agencies, regional organizations, and U.S. territories or possessions. Indian/Native American tribal governments that are not federally recognized are listed as eligible as well.
At the same time, the funding notice is clear about foreign involvement restrictions. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply. Non-domestic components of U.S. organizations are not eligible to apply, and foreign components (as defined by the NIH Grants Policy Statement) are not allowed under this opportunity. In practice, that means the applicant organization must be U.S.-based and the proposed project activities must not rely on a foreign component arrangement as part of the funded work.
The program is categorized as discretionary and uses the grant funding instrument, with activity categories spanning education, environment, food and nutrition, health, income security, and social services, reflecting the reality that structural racism and discrimination often operate through multiple sectors. The listing includes many CFDA numbers associated with NIH programs (including, among others, 93.113, 93.121, 93.172, 93.173, and additional NIH-related CFDA entries), which signals that the scientific scope can intersect with a wide range of NIH mission areas as long as the core focus remains on SRD and its impact on minority health and health disparities.
Key administrative details provided in the source data include the agency (NIH), a creation date of March 23, 2021, and an original closing date of August 24, 2021. The award ceiling shown is $500,000. The entry lists "ExpectedAwards:" but does not provide a number in the provided data, so the total number of anticipated awards is not specified in the excerpt.Apply for RFA MD 21 004
- The National Institutes of Health in the education, environment, food and nutrition, health, income security and social services sector is offering a public funding opportunity titled "Understanding and Addressing the Impact of Structural Racism and Discrimination on Minority Health and Health Disparities (R01 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.172, 93.173, 93.213, 93.233, 93.242, 93.273, 93.279, 93.286, 93.307, 93.310, 93.313, 93.361, 93.399, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.853, 93.855, 93.859, 93.865, 93.866, 93.867.
- This funding opportunity was created on 2021-03-23.
- Applicants must submit their applications by 2021-08-24. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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| Funding Opportunity |
|---|
| Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed) Apply for PAR 21 155 Funding Number: PAR 21 155 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $300,000 |
| Change of Recipient Organization (Type 7 Parent Clinical Trial Optional) Apply for PA 21 268 Funding Number: PA 21 268 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2021-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed) Apply for PA 21 262 Funding Number: PA 21 262 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2021-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) Apply for PA 21 259 Funding Number: PA 21 259 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2021-2 Omnibus Solicitation of the NIH and CDC for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required) Apply for PA 21 260 Funding Number: PA 21 260 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Limited Competition: Knockout Mouse Phenotyping Project Data Coordination Center and Database (UM1 Clinical Trial Not Allowed) Apply for RFA HG 21 037 Funding Number: RFA HG 21 037 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Limited Competition: Knockout Mouse Production and Phenotyping Project (UM1) Clinical Trial Not Allowed Apply for RFA HG 21 036 Funding Number: RFA HG 21 036 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Administrative Supplements to Promote Diversity in Small Businesses-SBIR/STTR (Admin Supp Clinical Trial Not Allowed) Apply for PA 21 345 Funding Number: PA 21 345 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Innovation Corps (I-Corps) at NIH Program for NIH and CDC Translational Research (Admin Supp Clinical Trial NOT Allowed) Apply for PAR 22 073 Funding Number: PAR 22 073 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Dissemination and Implementation Research in Health (R01 Clinical Trial Optional) Apply for PAR 22 105 Funding Number: PAR 22 105 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2022-2 Omnibus Solicitation of the NIH and CDC for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required) Apply for PA 22 177 Funding Number: PA 22 177 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $275,766 |
| PHS 2022-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed) Apply for PA 22 178 Funding Number: PA 22 178 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $275,766 |
| PHS 2022-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) Apply for PA 22 176 Funding Number: PA 22 176 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $275,766 |
| Maternal Health Research Centers of Excellence Data Innovation and Coordinating Hub/Resource Center (U24 Clinical Trial Not Allowed) Apply for RFA HD 23 036 Funding Number: RFA HD 23 036 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Maternal Health Research Centers of Excellence Implementation Science Hub/Resource Center (U24 Clinical Trial Optional) Apply for RFA HD 23 037 Funding Number: RFA HD 23 037 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Maternal Health Research Centers of Excellence (U54 Clinical Trial Optional) Apply for RFA HD 23 035 Funding Number: RFA HD 23 035 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $17,500,000 |
| Open Competition: Environmental influences on Child Health Outcomes (ECHO) Pregnancy Cohort Study Sites. Clinical Trial Not Allowed (UG3/UH3) Apply for RFA OD 22 017 Funding Number: RFA OD 22 017 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Environmental influences on Child Health Outcomes (ECHO) Laboratory Core (U24) Clinical Trial Not Allowed Apply for RFA OD 22 016 Funding Number: RFA OD 22 016 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Environmental influences on Child Health Outcomes (ECHO) Coordinating Center (U2C) (Clinical Trial Not Allowed) Apply for RFA OD 22 021 Funding Number: RFA OD 22 021 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Limited Competition: Environmental influences on Child Health Outcomes (ECHO) Cohort Study Sites for Pediatric Follow Up. Clinical Trial Not Allowed (UG3/UH3) Apply for RFA OD 22 019 Funding Number: RFA OD 22 019 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
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