Opportunity Information: Apply for RFA AG 24 047

The Grants for Early Medical/Surgical Specialists' Transition to Aging Research (GEMSSTAR) (R03 Clinical Trial Optional) funding opportunity (RFA-AG-24-047) is an NIH discretionary grant designed to help early-career physician-scientists in medical and surgical specialties, as well as early-career dentist-scientists, pivot into aging- and geriatrics-focused research. The program is intended to create a pipeline of future leaders in aging research by giving these clinicians a practical, supported way to develop a focused research direction, gain experience working across disciplines, and generate early evidence that can be used to compete for larger NIH aging awards later on. In other words, it is set up less as a long-term, fully powered project mechanism and more as a structured launchpad that helps clinicians build momentum in aging research.

The core purpose of the award is to fund small, transdisciplinary aging research projects that produce pilot data and hands-on research experience. The emphasis on "transdisciplinary" signals that NIH expects projects to draw from multiple fields or perspectives, which fits aging research well because aging-related problems often span clinical care, biology, population health, health services, and social or behavioral factors. The "Clinical Trial Optional" feature indicates applicants may propose studies that include clinical trials if appropriate, but a clinical trial is not required; applicants can pursue other forms of research that still advance aging or geriatric science and strengthen the investigator's trajectory.

From a funding details standpoint, the opportunity is categorized under the Health funding activity area and is associated with CFDA number 93.866. The funding instrument is a grant, and the mechanism is an R03, which typically aligns with smaller budgets and shorter, exploratory or developmental studies meant to establish feasibility and generate preliminary findings. The listed award ceiling is $100,000, reinforcing that the intent is to support a modest, focused project rather than a large multi-year trial. The opportunity record shows an original closing date of 2023-10-30 and a creation date of 2023-06-12.

Eligibility is broad and includes many common U.S. applicant organization types: state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities/Indian housing authorities; nonprofits with and without 501(c)(3) status (as long as they are not institutions of higher education in those categories); for-profit organizations (other than small businesses); and small businesses. The notice also explicitly calls out additional eligible applicant categories that NIH often highlights to encourage wide participation, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions. It also notes that Indian/Native American Tribal Governments other than federally recognized entities are included among the "other eligible applicants" categories.

Foreign eligibility is limited in a way that is common for many NIH opportunities. Non-domestic (non-U.S.) entities and non-domestic components of U.S. organizations are not eligible to apply as the applicant organization. However, foreign components are allowed as defined by the NIH Grants Policy Statement, meaning a U.S.-based applicant organization may include certain foreign collaborations or elements of work when justified and when they meet NIH's definition and requirements for a foreign component.

Overall, this opportunity is best understood as a targeted NIH aging research on-ramp for early-career clinicians in specialty fields who may have strong clinical training but need protected support and initial data to establish themselves in aging/geriatrics research. It is structured to help applicants run a manageable, well-scoped project that builds credibility, preliminary results, and cross-disciplinary experience, positioning them for more substantial aging research awards in the next stage of their careers.

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Grants for Early Medical/Surgical Specialists' Transition to Aging Research (GEMSSTAR) (R03 Clinical Trial Optional)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866.
  • This funding opportunity was created on 2023-06-12.
  • Applicants must submit their applications by 2023-10-30. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $100,000.00 in funding.
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQ)

What is the GEMSSTAR (R03 Clinical Trial Optional) funding opportunity?

The Grants for Early Medical/Surgical Specialists' Transition to Aging Research (GEMSSTAR) is an NIH discretionary grant opportunity (RFA-AG-24-047) that uses the R03 mechanism to support small, focused projects in aging and geriatrics research. It is designed as a practical launchpad for early-career clinician-scientists to build initial momentum in aging-focused research.

What is the main purpose of this award?

The main purpose is to fund modest, transdisciplinary aging research projects that provide hands-on research experience and generate pilot data. The program is meant to help early-career clinicians establish a clear aging/geriatrics research direction and build preliminary evidence that can later support applications for larger NIH aging awards.

Who is this opportunity intended to support?

This opportunity is intended to support early-career physician-scientists in medical and surgical specialties and early-career dentist-scientists who are transitioning or "pivoting" into aging- and geriatrics-focused research.

How should applicants think about the GEMSSTAR award in terms of career development?

Based on the description provided, GEMSSTAR is best viewed as an on-ramp into NIH aging research rather than a long-term mechanism for a fully powered research program. It is structured to help early-career clinicians develop a focused research trajectory, gain cross-disciplinary experience, and produce early results that strengthen future competitiveness for larger aging research awards.

What kinds of projects does GEMSSTAR fund?

GEMSSTAR funds small, transdisciplinary projects in aging and geriatrics research. The goal is feasibility and early evidence generation (pilot data), along with practical experience conducting aging-related research.

What does "transdisciplinary" mean in this context?

"Transdisciplinary" signals that NIH expects projects to integrate multiple fields or perspectives. Aging-related research often spans areas such as clinical care, biology, population health, health services, and social or behavioral factors, and projects are expected to reflect that broader, cross-cutting approach.

Are clinical trials required under this opportunity?

No. The opportunity is labeled "Clinical Trial Optional," which means applicants may propose studies that include clinical trials if appropriate, but a clinical trial is not required. Applicants may also propose other types of studies that advance aging or geriatric science and support the investigator's research trajectory.

What NIH grant mechanism is used for this opportunity?

The funding mechanism is an R03, which typically supports smaller budgets and shorter, exploratory or developmental studies intended to establish feasibility and generate preliminary findings.

What is the maximum award amount (award ceiling)?

The listed award ceiling is $100,000, reflecting the intent to support a modest, well-scoped project rather than a large, multi-year effort.

What is the funding activity area for this opportunity?

The opportunity is categorized under the Health funding activity area.

What CFDA number is associated with this opportunity?

The opportunity is associated with CFDA number 93.866.

What type of funding instrument is this?

The funding instrument is a grant.

When was this opportunity record created and when was it originally scheduled to close?

The opportunity record shows a creation date of 2023-06-12 and an original closing date of 2023-10-30.

What types of organizations are eligible to apply?

Eligibility includes a wide range of U.S. organization types, including:

  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public and state-controlled institutions of higher education
  • Private institutions of higher education
  • Federally recognized Native American tribal governments
  • Public housing authorities / Indian housing authorities
  • Nonprofits with 501(c)(3) status (other than institutions of higher education)
  • Nonprofits without 501(c)(3) status (other than institutions of higher education)
  • For-profit organizations (other than small businesses)
  • Small businesses

Are there additional applicant categories explicitly encouraged or listed?

Yes. The notice explicitly calls out additional eligible applicant categories NIH often highlights to encourage broad participation, including:

  • Alaska Native and Native Hawaiian Serving Institutions
  • Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)
  • Hispanic-serving Institutions
  • Historically Black Colleges and Universities (HBCUs)
  • Tribally Controlled Colleges and Universities (TCCUs)
  • Faith-based or community-based organizations
  • Eligible federal agencies
  • Regional organizations
  • U.S. territories or possessions
  • Indian/Native American Tribal Governments other than federally recognized entities (listed among the "other eligible applicants" categories)

Can a non-U.S. organization apply as the applicant?

No. Non-domestic (non-U.S.) entities are not eligible to apply as the applicant organization for this opportunity.

Can a U.S. applicant include a foreign collaboration or foreign work component?

Yes. While non-U.S. entities cannot be the applicant, foreign components are allowed as defined by the NIH Grants Policy Statement. This means a U.S.-based applicant organization may include certain foreign collaborations or elements of work when justified and when they meet NIH's definition and requirements for a foreign component.

Are non-domestic components of U.S. organizations eligible to apply?

No. Non-domestic components of U.S. organizations are not eligible to apply as the applicant organization.

What is the practical outcome NIH appears to be seeking through this program?

The program is intended to create a pipeline of future leaders in aging research by giving early-career clinicians a structured, supported way to build an aging/geriatrics research focus, gain experience working across disciplines, and produce early evidence that positions them to compete for larger NIH aging awards later.

Is this grant intended to fund large, fully powered studies?

No. The description emphasizes that it is not meant to be a long-term, fully powered project mechanism. The R03 structure and $100,000 award ceiling indicate it is meant for a manageable, focused project that builds feasibility and preliminary results.

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