Opportunity Information: Apply for PAR 19 098
The Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed), funding opportunity number PAR-19-098, is a National Institutes of Health (NIH) career development grant designed to support early-stage investigators based in low- or middle-income countries (LMICs) as they build the skills, research program, and professional trajectory needed to become independent, internationally recognized scientific leaders. The opportunity is a reissue of NIH's Emerging Global Leader Program and was updated specifically to align with NIH clinical trials policy, meaning the supported research under this particular announcement cannot include an independent clinical trial led by the awardee as the primary trial director.
A central feature of this opportunity is its strict eligibility structure focused on strengthening research capacity in LMIC-based institutions. Applications may be submitted only by non-U.S. entities (foreign institutions) located in countries classified as low- or middle-income. In contrast, non-domestic components of U.S. organizations are not eligible to apply as the applicant organization. At the same time, "foreign components" are allowed as defined by the NIH Grants Policy Statement, which generally means the project can include certain international elements or collaborations consistent with NIH rules, but the applicant institution itself must be an eligible LMIC-based foreign institution. The listing of eligible applicants includes public and state-controlled institutions of higher education, reflecting the emphasis on established academic or similarly structured research organizations capable of hosting a mentored career development program.
Programmatically, the K43 mechanism is meant to combine mentored research with structured career development activities. In practical terms, the award supports a period during which the recipient develops a focused research niche, builds a publication record, strengthens grant-writing and leadership skills, and establishes collaborations that position them to compete successfully for future independent research funding. While the title includes "Independent Clinical Trial Not Allowed," it does not mean clinical research is entirely excluded; rather, it indicates that the awardee cannot propose to serve as the lead for an independent clinical trial under this award. Depending on NIH policy details in the full announcement, related clinical research activities that do not meet the definition of an independent clinical trial, or participation in a trial led by another investigator, may be allowable, but applicants need to align their research plan with the specific clinical trial restrictions and definitions NIH uses.
Administrative details from the source indicate this is a discretionary grant opportunity offered by NIH under multiple CFDA listings (93.113, 93.121, 93.172, 93.242, 93.313, 93.398, 93.853, 93.989), reflecting that multiple NIH institutes and centers may participate or that the program aligns with several NIH funding lines. The original closing date shown is 2020-11-04, and the opportunity record was created on 2018-12-11. The award ceiling and expected number of awards are not specified in the provided data, which usually means applicants must consult the full funding announcement for budget limits, project period expectations, and institute-specific constraints.
Overall, PAR-19-098 is best understood as an NIH investment in long-term global research leadership: it targets talented investigators in LMIC institutions, provides a structured pathway toward research independence, and ensures compliance with NIH clinical trials policy by explicitly disallowing independent clinical trials within the scope of this K43 award. For eligibility and program fit, the determining factors are the applicant institution being a qualifying LMIC-based non-U.S. entity and the proposed career development and research plan being consistent with the "independent clinical trial not allowed" requirement.Apply for PAR 19 098
- The National Institutes of Health in the education, environment, health sector is offering a public funding opportunity titled "Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.172, 93.242, 93.313, 93.398, 93.853, 93.989.
- This funding opportunity was created on 2018-12-11.
- Applicants must submit their applications by 2020-11-04. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Public and State controlled institutions of higher education.
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 19 098) also looked into and applied for these:
| Funding Opportunity |
|---|
| Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Required) Apply for PA 19 121 Funding Number: PA 19 121 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Not Allowed) Apply for PA 19 122 Funding Number: PA 19 122 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Independent Scientist Award (Parent K02 - Independent Clinical Trial Required) Apply for PA 19 131 Funding Number: PA 19 131 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Independent Scientist Award (Parent K02 - Independent Clinical Trial Not Allowed) Apply for PA 19 132 Funding Number: PA 19 132 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| U.S.-China Program for Biomedical Collaborative Research (R01 Clinical Trial Optional) Apply for RFA CA 19 009 Funding Number: RFA CA 19 009 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $150,000 |
| Bioengineering Research Grants (BRG) (R01 Clinical Trial Not Allowed) Apply for PAR 19 158 Funding Number: PAR 19 158 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Summer Research Education Experience Program (Clinical Trials Not Allowed R25) Apply for PAR 19 164 Funding Number: PAR 19 164 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $100,000 |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33) Apply for PA 19 187 Funding Number: PA 19 187 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Summer Research Education Experience Program (R25 Clinical Trial Not Allowed) Apply for PAR 19 197 Funding Number: PAR 19 197 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $100,000 |
| Building Interdisciplinary Research Careers in Women's Health (BIRCWH); K12 Clinical Trial Optional Apply for RFA OD 19 020 Funding Number: RFA OD 19 020 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $600,000 |
| Basic and Translational Research on Adducts in Cancer Risk Identification and Prevention (R21 Clinical Trial Optional) Apply for PAR 19 252 Funding Number: PAR 19 252 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| Environmental Influences on Aging: Effects of Extreme Weather and Disaster Events on Aging Populations (R01 Clinical Trial Optional) Apply for PAR 19 250 Funding Number: PAR 19 250 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Basic and Translational Research on Adducts in Cancer Risk Identification and Prevention (R01 Clinical Trial Optional) Apply for PAR 19 251 Funding Number: PAR 19 251 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Dissemination and Implementation Research in Health (R21 Clinical Trial Optional) Apply for PAR 19 275 Funding Number: PAR 19 275 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| Mechanism for Time-Sensitive Research Opportunities in Environmental Health Sciences (R21 Clinical Trial Not Allowed) Apply for RFA ES 19 011 Funding Number: RFA ES 19 011 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| The Intersection of Sex and Gender Influences on Health and Disease (R01 Clinical Trial Optional) Apply for RFA OD 19 029 Funding Number: RFA OD 19 029 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44 Clinical Trial Not Allowed) Apply for PA 20 047 Funding Number: PA 20 047 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Development of Highly Innovative Tools and Technology for Analysis of Single Cells (STTR) (R41/R42 Clinical Trial Not Allowed) Apply for PA 20 025 Funding Number: PA 20 025 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Biomedical Data Repository (U24 - Clinical Trials Not Allowed) Apply for PAR 20 089 Funding Number: PAR 20 089 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Biomedical Knowledgebase (U24 - Clinical Trials Not Allowed) Apply for PAR 20 097 Funding Number: PAR 20 097 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
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